{"id":3507,"date":"2023-04-08T22:24:24","date_gmt":"2023-04-08T20:24:24","guid":{"rendered":"https:\/\/proyectoadicciones.com\/revista\/?post_type=glosario&p=3507"},"modified":"2023-04-08T23:00:05","modified_gmt":"2023-04-08T21:00:05","slug":"thc","status":"publish","type":"glosario","link":"https:\/\/proyectoadicciones.com\/revista\/glosario\/thc\/","title":{"rendered":"THC"},"content":{"rendered":"\n

F\u00f3rmula: <\/h2>\n\n\n\n

Tetrahidro-6,6,9-trimetil-3-pentil-6H<\/em>-dibenceno[b<\/em>,d<\/em>]piran-1-ol (C<\/strong><\/a>21<\/sub>H<\/strong><\/a>30<\/sub>O<\/strong><\/a>2<\/sub> <\/sup>)<\/p>\n\n\n\n

Definiciones:<\/h2>\n\n\n\n

El tetrahidrocannabinol<\/strong> (THC<\/strong>), tambi\u00e9n conocido como delta-9-tetrahidrocannabinol<\/strong> (\u03949<\/sup>-THC<\/strong>) es el principal constituyente psicoactivo<\/a> del cannabis<\/a>. La denominaci\u00f3n com\u00fan internacional<\/a> (DCI) del delta-9-tetrahidrocannabinol es dronabinol<\/strong> (bien sea de origen natural o sint\u00e9tico)<\/p>\n\n\n\n

Lo aislaron por primera vez en 1964 Habib Edery, Yechiel Gaoni y Raphael Mechoulam<\/a>, del Instituto Weizmann de Ciencias<\/a>, en Rejovot, Israel. En estado puro, es un s\u00f3lido v\u00edtreo a bajas temperaturas, y se torna viscoso y pegajoso al calentarlo. El THC es poco soluble en agua, pero se disuelve f\u00e1cilmente en la mayor\u00eda de disolventes org\u00e1nicos, espec\u00edficamente l\u00edpidos y alcoholes.<\/p>\n\n\n\n

Se cree que el THC del cannabis est\u00e1 involucrado en el mecanismo de autodefensa de la planta, tal vez contra herb\u00edvoros, pero por ahora a\u00fan se desconoce su funci\u00f3n. El THC tambi\u00e9n posee altas propiedades de absorci\u00f3n de UV-B (280\u2013315 nm); se ha sugerido que podr\u00eda proteger a la planta de la exposici\u00f3n nociva de la radiaci\u00f3n UV.<\/p>\n\n\n\n

Sus efectos farmacol\u00f3gicos son el resultado de su vinculaci\u00f3n con los receptores espec\u00edficos CB1 y CB2, situados tanto en el cerebro como en diversas partes del cuerpo (pulmones, h\u00edgado y ri\u00f1ones). Dado que el cuerpo no produce naturalmente cannabinoides<\/a>, los investigadores comenzaron por averiguar cu\u00e1l es la sustancia natural que se enlaza con estos receptores, lo que llev\u00f3 al descubrimiento de la anandamida<\/a> y de otras sustancias implicadas en este proceso.<\/p>\n\n\n\n

Probablemente, sea su afinidad con las sustancias lipof\u00edlicas<\/a> lo que haga que el THC se adhiera a la membrana de las c\u00e9lulas (principalmente neuronales).<\/p>\n","protected":false},"excerpt":{"rendered":"

Sus efectos farmacol\u00f3gicos son el resultado de su vinculaci\u00f3n con los receptores espec\u00edficos CB1 y CB2, situados tanto en el\u00a0cerebro\u00a0como en diversas partes del cuerpo (pulmones, h\u00edgado y ri\u00f1ones). <\/p>\n","protected":false},"featured_media":0,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[],"class_list":["post-3507","glosario","type-glosario","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/glosario\/3507","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/glosario"}],"about":[{"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/types\/glosario"}],"version-history":[{"count":0,"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/glosario\/3507\/revisions"}],"wp:attachment":[{"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/media?parent=3507"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/proyectoadicciones.com\/revista\/wp-json\/wp\/v2\/categories?post=3507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}